BizTalk 2020 come out last week, you can find the details here
There are Adapters fixes for 2 x WCF-SAP, WFC-OracleDB, Office365 (Outlook & TMS) & Event Hub.
For the runtime FIX: Excessive CPU usage in kernel mode of Windows when you run multiple BizTalk host instances
A fix for how maps treat whitespaces, this one a fix for where it ignored the default element value if it was only whitespace. FIX: Default element value of spaces or tabs is ignored when using the .NET transform engine in a BizTalk map
A FIX: Turning on auditing causes errors in the BizTalk Server Administration Console
Also of note are the version of components you will need.
Updated External Dependencies
If you have BizTalk Developer Tools installed, you must install the latest version of BizTalk Server Visual Studio extension (build 22.214.171.124) in addition to this CU package. The extension can be installed from https://marketplace.visualstudio.com/items?itemName=ms-biztalk.BizTalk or from within Visual Studio through Manage Extensions.
Always check Service Pack and cumulative update list for BizTalk Server for the latest CU for both core BizTalk and Adapters for Enterprise Applications, for HIS check HIS Update Center