After the July security patches from the 10th, not only did we have BizTalk issues we also hit the error the following error after doing a IIS Reset. “The service did not respond to the start or control request in a timely fashion. (2147943453, 8007041d).”

See this thread IISRESET results in W3SVC stuck in stopping status after July 2018 patches that has some details about it.

According to that thread, it looks like Microsoft already has Mitigation patches for this issue already (released on the 17th).

Windows Server 2008 SP2 KB4345397

Windows Server 2008 R2, KB4345459

Windows Server 2012 KB4345425.

Windows Server 2012 R2 KB4345424

Windows Server 2016 KB4345418